Laboratory Manager- Drug Metabolism and Disposition in Silver Spring, MD at General Dynamics Information Technology

Date Posted: 7/2/2020

Job Snapshot

Job Description

GDIT is seeking a Laboratory Manager to support the Walter Reed Army Institute of Research (WRAIR) Experimental Therapeutics Branch’s Drug Metabolism and Disposition Section.

RESPONSIBILITIES:Establish and maintain a means to receive and track the processing of all samples submitted to the lab, and coordinate the scheduling of experiments and use of instrumentation to facilitate the timely turnover of data to research personnel.Maintain laboratory supply and reagent inventory to fully support the ongoing and upcoming research needs of the lab, and proactively submit purchase requests for needed research supplies and reagents such that there be no delay to scheduled research.Participate in the research budget planning and proposal submission process to provide input for estimating cost of supplies and reagents and estimating instrumentation-time needed to support proposed research such that all estimates proposed for supplies and reagents are determined to be 90% accurate at the end of the performance period.Maintain an internal budget of all purchase requests submitted and line of accounting used, and match these records with weekly budget reports from the resource management division in order to account for any items not received and ensure that all planned supply and reagent resources have been at least 90% committed by end of the period of performance or cutoff date established during the planning process.Be proficient in the use of government procurement systems (specifically GFEBS and DMLSS) such that purchase requests and subsequent tracking within these systems is available throughout the contractual period.Train and assist technicians and junior researchers.Prepare and use laboratory SOPs and protocols.Plan, coordinate, and perform LC-MS analyses in support of pharmacokinetic studies and chemical purity determinations.Use LCMS systems from different manufacturers.Write new and troubleshoot existing scripts for the performance of assays utilizing the TECAN Liquid Handling system.Oversee scheduling of all laboratory operations, including, but not limited to, manpower schedules, instrument usage, maintenance, and miscellaneous laboratory duties.Maintain a Microsoft Access database for the logging of sample receipt, required testing, special requests, and preliminary results.Assist in the writing of manuscripts for publications, prepare data for in-house presentations, and present findings at scientific meetings.Comply with all specified guidelines regarding safety, security, standard operating procedures, written protocols, technical manuals, and procurement of supplies/equipment as per WRAIR regulations.Maintain appropriate data records and QC data for incorporation into LIMs database.

QUALIFICATIONS:Required Skills and Experience:MS or Ph.D. degree or appropriate combination of education3+ years experience using/managing mass spectrometry systems for the characterization of chemical entities.Experience in handling laboratory samples, troubleshooting and maintaining laboratory equipment, analyzing data using applicable software, generating reports and summaries for presentations, managing data spreadsheets, requesting supplies and materiel as needed to perform general laboratory maintenance.Experience using government procurement systems and submitting purchase requests within these systems. Have laboratory management experience.Laboratory budget experience and knowledge of cost of supplies used in support DMPK research.

ATTRIBUTES FOR SUCCESSExcellent organizational and interpersonal skills as well as good written and oral communication.

Work Environment:Laboratory/office environment; may require working evenings and weekends.

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GDIT is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status, or any other protected class.